Mechanisms Involved in Maintenance of Fluid and Electrolyte Balance
From pEx
Defense of Tonicity[edit]
- Defense of ECF tonicity is primarily the function of vasopressin-secreting and thirst mechanism
- When the effective osmotic pressure of plasma rises, vasopressin secretion is increased and thirst is stimulated
- When plasma becomes hypotonic, vasopressin secretion is decreased and solute-free water is excreted
- In health, plasma osmolality ranges from 280-295mOsm/kg of H2O, with vasopressin maximally inhibited at 285mOsm/kg, and stimulated at higher values
- Vasopressin increases the per
