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  1. Examiners Reports
  2. Primary exam requirements

2.2.1 General anaesthesia and sedation


  1. Drug Actions
  2. Receptor Activity
  3. Dose-Effect Relationships
  4. Efficacy and Potency
  5. Mass Action, Affinity and Dissociation
  6. Mechanisms of Adverse Drug Effects


  1. The Compartment Model and Definitions
  2. Absorption
  3. Factors Influencing Drug Distribution
  4. Drug Clearance Mechanisms
  5. Drug Metabolism
  6. IV and Infusion Kinetics
  7. Drug Monitoring

2.2.3 Regional and local anaesthesia

  1. The Physiology of Nerve Conduction
  2. Physiological Consequences of Central Neuraxial Blocks
  3. Pharmacology of Local Anaesthetics
  4. Anatomy of the Vertebral Column, Spinal Cord and Meninges
  5. Describe the Dermatomal Innervation
  6. Describe the Myotomal Innervation
  7. Describe the Pain and Sensory Pathways
  8. Principles of Ultrasound Imaging and the Safe Use of Ultrasound Equipment for Regional Anaesthesia
  9. Principles of Nerve Stimulation to Locate Nerves and the Safe Use of Nerve Stimulators

2.2.4 Perioperative medicine

Respiratory anatomy and physiology

Model Answers

  1. Chest Wall & Diaphragm
  2. Lower Airway Anatomy
  3. Anatomy of Pulmonary and Bronchial Circulation
  4. Control of Ventilation and Alteration in Anaesthesia
  5. Nature and Function of Surfactant
  6. Lung Compliance and Elastic Properties
  7. Fast and Slow Alveoli, and Time Constants
  8. Chest Wall and Pressure/Volume Relationships of Lung/Chest Wall
  9. Vertical Pleural Pressure Gradient and its Significance
  10. Gas Flow and Resistance Physics in the Lung
  11. Airway Resistance and its Measurement
  12. Closing Capacity
  13. Work of Breathing
  14. Altered Lung Mechanics in Disease
  15. Lung Volumes/Capacities and their Measurement
  16. Dead Space and Bohr/Alveolar Gas Equations
  17. Composition of Ideal Alveolar/Mixed Expired Gas
  18. Oxygen Cascade
  19. Alveolar Exchange of CO2 and O2
  20. Diffusion Capacity
  21. Normal VQ Matching
  22. West Lung Zones
  23. Shunt Equation
  24. VQ Mismatch and Venous Admixture
  25. Oxygen Carriage and Storage
  26. CO2 Carriage and Storage
  27. Pulmonary and Systemic Circulation Differences
  28. Pulmonary Vascular Tone and Resistance
  29. Physiological Consequences of IPPV and PEEP
  30. Physiological Effects of O2, CO2 derangement and CO
  31. Discussion of Factors Affecting Ventilation
  32. Define Humidity and Importance of Humidification
  33. Non-Ventilation Lung Functions

Respiratory Pharmacology

  1. Pharmacology of Anti-Asthma Drugs
  2. Pharmacology of Drugs used in Pulmonary Hypertension
  3. Oxygen Therapy

Renal Fluid and Electrolytes

  1. Functional Anatomy of Kidneys and Urinary Tract
  2. Physiology of Renal Blood Flow
  3. Glomerular Filtration and Tubular Function
  4. Counter-Current Mechanisms in the Kidney
  5. Mechanisms of Renal Function Regulation
  6. Endocrine Functions of the Kidney
  7. The Kidney in Glucose, Nitrogenous Waste Products and Drugs
  8. Measuring Glomerular Filtration Rate and Renal Blood Flow
  9. Physiological Effects and Clinical Assessment of Renal Dysfunction
  10. Renal Response to Hypovolaemia
  11. Effects of Anaesthesia on Renal Function
  12. Function, Distribution and Physiological Importance of Sodium, Potassium, Magnesium, Calcium and Phosphate Ions
  13. Mechanisms Involved in Maintenance of Fluid and Electrolyte Balance
  14. Constituents and Functions of Plasma
  15. Regulation of Osmolality
  16. Significance of Oncotic Pressure, Colloid Osmotic Pressure and Reflection Coefficients
  17. Regulation of Acid/Base Balance
  18. Acid-Base Chemistry Using the Henderson-Hasselbach equation and Strong Ion Difference

2.2.5 Pain medicine


  1. Pain/Sensory Pathway Anatomy
  2. Autonomic Nervous System Anatomy
  3. Physiological Mechanisms of Pain
  4. Progression from Acute to Chronic Pain
  5. Injury Response to Acute Pain
  6. Applied Pathology/Psychology of Neuropathic Pain
  7. Effects of Pain/Analgesia on Injury-Induced Organ Dysfunction
  8. Pain Physiology/Peception in the Older Patient